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(1) Chronic NTG injection induced a dramatic increase in GLP-1R in TNC microglia

It is non-addictive and preserves the complete physiology of the sleep-wake cycle

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AOMs that mimic glucose-dependent insulinotropic polypeptide (GIP) Due to the relatively weak insulinotropic effect observed in patients with T2DM, in addition to the preclinical data on GIP receptor (GIPR) agonism in mice with diet-induced obesity, the use of GIPR agonists (GIPRAs) for the treatment of T2DM and obesity was initially viewed with skepticism (74)