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The absolute risk appears to be rare based on clinical trial and post-marketing data
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One of the most notable investigations, the STEP 1 trial published in The New England Journal of Medicine, reported that participants receiving weekly GLP1-S alongside lifestyle interventions experienced an average 14.9% decrease in body weight across 68 weeks[7][8]
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Omeprazole, when used long-term, can also impact kidney health, increasing the risk of chronic kidney disease in some people
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