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In other body tissues, extracellular fluid is generated through capillary leakage

For moderate IPTB, NAC oral dose (ACC long, 600 mg, Hexal), prepared by University Hospital of Nantes Pharmacy, was administrated at 3.6 g/d (80 mg/kg of body weight (BW)/d) in 6 doses from day 0 to day 7, followed by 1.8 g/d per os (40 mg/kg BW/d) from day 8 until 37th weeks of GA or delivery, whichever occurred first

While not dangerous, they indicate significant vascular reactivity and suggest the nitric oxide system is responding robustly to the peptide

Coelho AM, Queiroz IF, Lima WG, Talvani A, Perucci LO, de Souza O, M., Costa DC