The search strategy combines Medical Subject Headings (MeSH) and keywords including GLP-1, glucagon-like peptide-1 receptor, GLP-1 receptor agonist, sepsis, systemic inflammation, infection, immune response, critical illness, MODS, multiple organ dysfunction, cytokines and sepsis treatment. Articles were screened for relevance based on titles and abstracts, with full-text evaluation of studies addressing the mechanistic or therapeutic implications of GLP-1 signaling in experimental or clinical models of sepsis
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Intermittent claudication in peripheral arterial disease In peripheral arterial disease, atherosclerosis of the arteries that supply the lower extremities may diminish blood flow to the point that the metabolic needs of exercising muscles are not sufficiently met, thereby leading to ischemic leg or hip pain known as claudication (see the page on Intermittent Claudication in Peripheral Arterial Disease) (63)
meditation or a hot shower) Going to bed at the same time every night Keeping your bedroom dark, quiet, cool, and comfortable Limiting screen time before bed / no screen time for at least an hour before your bedtime ritual Waking up at the same time every day, including on weekends Avoiding caffeine after 12:00 pm Avoiding naps Avoiding late-night meals 4 - Stay Mentally Active Treat your brain like any other muscle, use it to not lose it