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Two-bag intravenous N-acetylcysteine, antihistamine pretreatment and high plasma paracetamol levels are associated with a lower incidence of anaphylactoid reactions to N-acetylcysteine
After four weeks, the dose is increased to 0.5 mg
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If glutathione levels increase but MDA remains elevated, the issue may be mitochondrial function or inflammatory cytokines rather than antioxidant capacity specifically
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