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For example, 70 mg efruxifermin dosed weekly, corresponding to two pharmacokinetic half-lives, appeared to improve HOMA-IR, fasting glucose, and fasting insulin in type 2 diabetes patients (246)
This study further developed a cell death-related signature (CDS) based on CASP1, CYBB, PLA2G4A, and CTSS, providing an effective diagnostic tool that tightly correlates with progressive renal function decline and local immune microenvironment remodeling (135)
Biomedicines 11 , 669 (2023)
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