Although malonyl-CoA and long-chain acyl-CoA are believed to regulate GSIS, abrogation of malonyl-CoA formation by overproducing malonyl-CoA decarboxylase in beta cells did not interfere with GSIS, [58] whereas chronic, but not acute, suppression of ACC production by 6080% in INS-1 832/13 cells and isolated islets significantly reduced GSIS [59]
[PMID: 18713618] PubMed record related to this compound for laboratory literature review
Karem Salem, Fayoum University, Egypt Updates Copyright 2020 Pina, Borges, Meneses, Branco, Birne, Vilasi and Macedo
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