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The formation of such antibodies could theoretically increase allergy risk over time, but the published data does not indicate concerning rates of antibody development that would suggest emerging immunogenicity problems
doi: 10.1016/j.pnpbp.2022.110580, 110 O'ConnorE
This is in line with higher proportions of HOSC observed in the S-phase of cell cycle during flow cytometry analysis as both CCND2 and CDK6 are important regulators of G1/S phase of cell cycle [44]
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