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Parker, R.S., Sontag, T.J., Swanson, J.E., 2000
Native IGF-1 binds IGFBP-3, the dominant carrier protein in circulation, with a dissociation constant in the low nanomolar range (Kd approximately 0.1 to 1 nM in most published binding assays)
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Therefore, the aim of this work is to critically summarize current experimental and clinical observations and to discuss plausible, but still speculative, mechanisms by which SGLT2 inhibitors might influence thyroid function, rather than to suggest established clinical benefits
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