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123 showed the difference between pharmacokinetic profiles in premature newborns compared with adults, and despite the small sample size, they concluded that it is possible to obtain and maintain high serum concentrations using a single administration of melatonin repeated every 24/48 h
Webb CB, Lehman TL, McCord KW
Access this article Similar content being viewed by others Abbreviations AAPH: Hydrochloride 2,2-azobis-2-amidinopropane AIDS: Acquired immunodeficiency syndrome ARE: Antioxidant response element CAT: Catalase Cu/Zn-SOD: Copper/zinc-superoxide dismutase DIVEMA: Divinyl ether and maleic anhydride DNA: Deoxyribonucleic acid EC-SOD: Extracellular-superoxide dismutase Fe-SOD: Iron-superoxide dismutase FIV: Feline immunodeficiency virus GPx: Glutathione peroxidase H 2 O 2 : Hydrogen peroxide HIV: Human immunodeficiency virus HO: Hydroxyl radical Mn-SOD: Manganese-superoxide dismutase Nrf2: Transcription factor nuclear-factor-E2-related factor O 2 - : Superoxide anion radical PEG: Pegylated PMA: Phorbol 12-myristate 13-acetate ROS: Reactive oxygen species SOD: Superoxide dismutase REFERENCES Davies KJA
