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This is a real game-changer for the development of GLP-1 RAs and peptide therapeutics more broadly
They act on different receptors
The really noticeable difference, however, should be in terms of appetite and food consumption
Other findings included: Gallbladder issues (especially with rapid weight loss) Pancreatitis (rare, with unclear causality) Thyroid C-cell hyperplasia (in animals, not seen in humans) Lean mass lossup to 40% of weight lost may be muscle in older adults None of these derailed regulatory approvals
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