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There are no major contraindications identified with GHK-Cu, and it is considered safe for extended use
With large surface asperities (surface roughness, surface projections), air is trapped between textured grooves, creating air pockets between liquid and surface and dramatically reducing the fraction of surface-liquid contact (Cassie-Baxter state) [5]
Some users take the product ongoing for maintenance
Mildly acidic solutions such as dilute acetic acid are sometimes used for peptides that resist dissolving, while a few require a very small volume of sodium hydroxide or a similar agent
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