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The advancement occurred with the creation of exenatide, originating from exendin-4, a substance found in Gila monster saliva that inherently resisted DPP-4 destruction (Furman 2012)
Nasal delivery can be appealing for patients who prefer an option that avoids both oral and injectable routes, while injections provide a more direct method of administration
Traditional BMI misses key factors like muscle mass and body composition
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