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Most participants tolerated the medication well by the end of the study period
At the standard titration steps thats roughly 40 u (2 mg), 80 u (4 mg) and 160 u* (8 mg) on a U-100 insulin syringe (*split doses above 100 u into two injections)
"Nitrous oxide has multiple deleterious effects on cobalamin metabolism and causes decreases in activities of both mammalian cobalamin-dependent enzymes in rats"
Do not take an additional dose, skip future doses, or change your prescribed amount in response to a symptom unless your healthcare provider gives you specific instructions
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