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It was developed by Novo Nordisk in the mid-1990s as part of a research program investigating selective growth hormone secretagogues
Common side effects are mild: Injection site irritation Mild headache Transient flushing Slight appetite changes Serious adverse effects are uncommon with appropriate dosing and medical supervision
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In a randomized controlled trial, 11 obese participants received a dietary intervention that reduced their intake by 1,000 kcal, after 16 weeks their peripheral insulin sensitivity enhanced
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