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El estudio SELECT, realizado con SEMA 2,4mg, mostr coherentemente una reduccin de eventos cardiovasculares adversos mayores (major adverse cardiac events [MACE]) de triple objetivo compuesto (infarto de miocardio no mortal, accidente cerebrovascular no mortal, mortalidad cardiovascular) del 20% respecto a placebo en una poblacin con enfermedad cardiovascular establecida e IMC superior a 27kg/m2 sin diabetes tras 39,8meses de seguimiento23

Cancer cell biology research examining IGF1R-driven proliferation often uses LR3 as a standard reagent precisely because the dose-response across a multi-day proliferation assay is more interpretable when the ligand is stable in the media

A1 astrocytes show a neurotoxic profile, contributing to synaptic loss, whereas A2 astrocytes exhibit neuroprotective properties