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One practical advantage of evening timing is consistency with your weekly scheduleyou're more likely to remember your injection on the same day and time each week if it fits a predictable evening routine

Injection site rotation: Move sites week to week (abdomen, thighs, upper arms), keeping each shot at least 1 inch from the last to limit irritation and prevent lipohypertrophy [15]

The combination of fever, jaundice, and right upper quadrant pain (Charcot's triad) suggests cholangitis, a medical emergency requiring immediate care

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