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Studies have shown that when amyloid-beta and tau are increased, the cells ability to neutralize oxidative stress and mitochondria specific ROS is decreased leading to further tau hyperphosphorylation and neurodegeneration ( These redox imbalances also impact astrocytes, which normally synthesize GSH through the consecutive sections of two ATP consuming cytosolic enzymes
Immune Function: GSH supports immune function by modulating immune cell activity, including lymphocyte proliferation and cytokine production
Bar-Sela G, Wollner M, Hammer L, Agbarya A, Dudnik E, Haim N
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