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The authors systematically searched PubMed and Embase from inception to 1 May 2025 for cohort studies comparing the effect of combination therapy with SGLT2 inhibitor or GLP-1 RA monotherapy on (cardiovascular) mortality and cardiovascular or kidney endpoints in individuals with type 2 diabetes

Key Takeaway: Since you no longer have a gallbladder, you are not at risk for the gallstones or gallbladder inflammation sometimes associated with rapid weight loss or GLP-1 therapy

The role of LKB1/AMPK, KEAP1, and GSK3 in the impairment of the NRF2 response

Hydration : Proper hydration enhances the supplements effects and supports digestion