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Probiotics are available as capsules, powders, and fermented foods (such as live yoghurt, kefir, and sauerkraut), though supplemental forms provide more standardised dosing
They commonly appear on the inner lining of the cheeks (buccal mucosa), but can also develop on the roof of the mouth (palate), gums, inner lips, and other oral surfaces
Important safety considerations include an increased risk of hypoglycemia when used with insulin or sulfonylureas, and a boxed warning about thyroid C-cell tumors (contraindicated in patients with personal/family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2)
These mechanisms are detailed in Figure 3A
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