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GI-related adverse events were most prevalent during the first week of treatment, with observed rates generally declining through the remainder of the study
Clinical trials show gastrointestinal side effects occur in approximately 25-30% of patients, with diarrhea being one of the most commonly reported GI symptoms alongside nausea and constipation
Evidence now challenges the conventional six-month wait period before initiating anti-obesity medications, pointing instead toward earlier pharmacological intervention at just one month after behavioral therapy begins
That does not make an unapproved drug safe
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