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doi: 10.3389/fphar.2021.697442 Received 19 April 2021 Accepted 31 May 2021 Published 14 June 2021 Volume 12 - 2021 Edited by Valentina Vellecco, University of Naples Federico II, Italy Reviewed by Jens Juul Holst, University of Copenhagen, Denmark Venkateswarlu Kanamarlapudi, Swansea University, United Kingdom Updates Copyright 2021 Xie, Chen, Xu, Han, Hu, Chen, Zhang and Ding

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originates from the Pacific islands and is a popular plant in Brazil and India (Chan and Wong, 2015)