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Description

The ventral tegmental area (VTA), the nucleus accumbens (NAc), and the prefrontal cortex (PFC) all contain GLP-1 receptors

Although the study was not powered to assess cognitive changes, researchers found that patients who received liraglutide had an 18% slower decline in cognitive function in a year compared to those who got the placebo

References Insel TR, Cuthbert BN

These changes can lead to temporary energy crashes, especially during the initial adjustment period, which typically lasts a few weeks to a couple of months and may make these symptoms more pronounced