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While growth and sexual development in WT cells faltered early with lower levels of erastin treatment, parasites grown in SQLE -KO cells were much more resistant to erastin (Fig 4D)
Taking it between meals, when enzyme activity is diminished, may increase the chance of intact absorption [1]
BSO is an inhibitor of GSH synthase that has been used to deplete GSH in vitro , including in macrophages ( We analyzed the gene expression profile and identified patterns of LPS-induced genes that were inhibited by endogenous GSH or that, on the contrary, required GSH for their induction
doi: 10.1016/j.pharmthera.2021.107916 216 Prez de la LastraJ
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