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Secondly and thirdly, we did two analyses to assess the potential effect of informative censoringone analysis using time varying inverse probability of censoring weighting to account for censoring due to drug switching or discontinuation between the two exposure groups, mortality, and administrative censoring during the follow-up and one analysis using an intention-to-treat exposure definition (that is, patients were followed regardless of treatment discontinuation or switching) with up to one year of follow-up (which was implemented to minimise the effect of exposure misclassification in this analysis)

By integrating molecular, preclinical, and clinical findings, this review proposes that convergent dysregulation of trophic and metabolic signaling pathways may contribute to ASD heterogeneity

Tirzepatide (Mounjaro), a dual GIP/GLP-1 receptor agonist, shows dose-dependent nausea rates, ranging from approximately 12-18% at lower doses to higher rates at doses used for weight management, as demonstrated in the SURPASS-2 trial comparing it with semaglutide

Neuroscience 250 , 2030 (2013)