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The pulsatile nature of GH release induced by this combination, rather than continuous elevation, has been identified as a key factor in maintaining receptor sensitivity and avoiding desensitization artifacts that can complicate long-term research protocols

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sparse but functional cardiac GCGR engagement drives the dose-scaling excess (36 bpm) unique to this class

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Hunger increases

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10.1016/j.diabres.2006.12.009 146 PintoL

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