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Some patients report feeling physically full yet energetically depleted
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For future studies, it is recommended to select earlier time points and a higher frequency to assess gene expression and mitochondrial functionality of PBMC following an LPS challenge, as the primary dynamics of the immune response occur immediately after the immune challenge
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Recent advancements in sustained-release formulations, like PLGA nanoparticles for delivering exendin-4, show promise in preclinical models but still require validation in human studies (Wang et al., 2023)
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