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Approval: 1991 WARNING: SUICIDAL THOUGHTS AND BEHAVIORS See full prescribing information for complete boxed warning
Until just a few years ago, doctors really didnt have anything that worked, says Clyde Yancy, chief of cardiology at the Northwestern University Feinberg School of Medicine in Chicago
It increases the risk of diabetes, high blood pressure, heart disease, and joint problems
In addition, current evidence gaps exist due to lack of research stan-dardization in examining symptom clusters, incomplete research on herbal toxicity and safety, insufficient evidence for direct antitumor activity of herbs (relying mostly on pre-clinical data), few high-quality RCTs to validate their clinical efficacy, and studies in homogeneous populations (Asian) lacking generalizability [58]
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