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One participant with a history of depression experienced a new episode of depression during the study with an associated increase in PHQ-9 of from 15 to 20 points despite an initial sense of increased resilience
The RNA-binding protein SND1 promotes the degradation of GPX4 by destabilizing the HSPA5 mRNA and suppressing HSPA5 expression, promoting ferroptosis in osteoarthritis chondrocytes
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