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Regulation of insulin secretion in human pancreatic islets
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The cerebrovasculature is a very bioenergetically active tissue with capillary endothelial cells having been shown to possess five times more mitochondria than muscle cells (Oldendorf and Brown, 1975) and transport 10 times their weight in glucose each minute across the BBB, along with accomplishing other energetically costly cellular processes ( APOE -driven differences in FAO in both larger and smaller vessels that can affect transport functions
