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Current records estimate an annual global average of 30 million cardiac dysfunction cases, and experts anticipate that number to rise over the next 30 years
The pathogenesis and the pathophysiology of sepsis is very complicated and multifaceted: numerous biological mechanisms, such as infection, inflammation, oxidative stress, immune system dysregulation, blood coagulation, endothelium dysfunction, tissue damage, elevated cellular death and/or apoptosis are involved during sepsis at tissue, cellular and molecular levels causing a damaging systemic reaction [379]
Long-lasting blood-brain barrier dysfunction and neuroinflammation after traumatic brain injury
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