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A study conducted at the University of North Carolina found that methionine solutions stored at 25C for 48 hours retained only 68% of their initial methyl donor capacity when tested in hepatocyte cell cultures
Additionally, the cyclic trisulfide structure of LASSS, as opposed to the linear trisulfides such as GSSSG and cysteine trisulfide (Cys-SSS-Cys), could guarantee the unique reactivity of LASSS (see again Figure 1a for chemical structures)
The authors concluded that the oral nutritional supplement containing collagen peptides reduced skin vulnerability in older adults and prevented skin tears with senile purpura [33]
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