Goal: Support metabolic efficiency through NNMT inhibition, potentially enhancing fat oxidation and NAD+ levels [1] [2]
Contrasting with these actions of GIPR activation to reduce food intake, Gipr knockout (KO) mice, and humans with impaired function GIPR variants, are protected against obesity, also probably through a central effect, as similar observations were made in global KO mice or mice lacking Gipr in nestin, synapsin or VGAT-expressing cells 4,5,9,10,11,12
If chronic inflammation and impaired tissue remodeling are central, TB-500's anti-inflammatory and migration-enhancing effects are more directly relevant
Many clients report noticeable improvementssuch as more energy, enhanced clarity, and improved skin tonewithin days