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Lifestyle flexibility is one advantage of weekly injectable GLP-1 therapy compared to daily oral medications
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Express Scripts requires BMI of 30 or higher, or BMI of 27 or higher with at least one weight-related comorbidity (type 2 diabetes, hypertension, dyslipidemia, obstructive sleep apnea, or cardiovascular disease)
In contrast, semaglutide, liraglutide, and dulaglutide undergo proteolytic degradation with minimal renal clearance, making them suitable options for patients with renal impairment, though caution is still advised
