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den Heijer M, Koster T, Blom HJ, Bos GMJ, Brit E, Reitsma PH, Vandenbroucke JP, and Rosendaal FR (1996)
Identification of caspase-8 as a cell fate-regulating enzyme in mature erythrocytes might have far-reaching implications for RBC biology, since the ability to regulate and select cell death modalities questions a conceptual view on erythrocytes as entities existing in a state between life and death
In this experiment, calibrated Von Frey filaments were employed to evaluate joint pain sensitivity as previously described 38,39 , the results showed that metformin treatment increased the paw withdrawal thresholds compared with those in MIA-induced OA model group (Fig
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