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Jimenez V, Jambrina C, Casana E, Sacristan V, Muoz S, Darriba S, Rod J, Mallol C, Garcia M, Len X et al

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Compared with normal skin fibroblasts, a greater number of keloid fibroblasts displayed a senescent phenotype and were arrested at the G0/G1 phase using a serum-limited culture approach, indicating the senescent tendency of keloid fibroblasts under simulated ischemic stress

DSIP is classified as a neuromodulatory peptide because it influences both neuroendocrine signaling and neurotransmitter activity