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The effect is feeling full sooner and for longer, not a structural change
GLP-1R activation can induce proximal tubular natriuresis via inhibition of sodium/hydrogen exchanger isoform 3
We describe the use of glutathione (GSH) for this purpose, which is present at elevated levels (10 mM) in various cancer cells [7]
This favorable safety margin provides reassurance, though extrapolation from animals to humans always involves uncertainty
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