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Cleve Clin J Med 2010

However, some users report cardiovascular effects including rapid heartbeat, chest pain, or dizziness, particularly with excessive application or use on compromised skin barriers

Among these, autosomal dominant forms include mutations in SNCA (PARK1), UCHL1 , LRRK2 (PARK8), CHCHD2 , GBA , and VPS35 (PARK17), whereas autosomal recessive forms involve PARK2 (parkin), PINK1 (PARK6), DJ-1 (PARK7), and ATP13A2 (PARK9) (260)