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With the evolving evidence and guidelines across the world, we should now choose second-line agents such as SGLT2i and GLP1-RAs with proven CV benefits in patients with high CV risk followed by agents with proven CV safety if additional glycemic control is required
Semaglutide is a specific GLP-1 receptor agonist (GLP-1 RA) a medication that mimics the action of natural GLP-1 but with important modifications: Extended half-life: Semaglutide is engineered to resist degradation by DPP-4, allowing it to remain active in the body for approximately 7 days, compared to just minutes for natural GLP-1
Because of that, planning ahead is critical
Beta-alanine works really well for activities that need sustained effort
