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Then, an electric current of 0.1 mA/10 g of body weight was applied throughout
It was concluded that the C max and AUC changes of digoxin after GLP-1 RA administration may not be clinically significant
This effect is most pronounced after initiation and may diminish somewhat with chronic use
Although an increase in heart-rate per se is not a major problem for most people, it is salient in the case of GLP1R, GIPR or GR agonists since the target patient population of these agonist are obese patients, who likely already suffer from cardiovascular complications
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