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Differences in treatment response may be indicative of differences in etiologies and mechanisms, like neuroinflammation, changes in the neuroendocrine system, or alterations in the gut microbiome (Mousten et al., 2022)

Mol Nutr Food Res (2011) 55(11):165565

A thorough weight history, assessment of volume status and use of three essential tests (blood pressure, estimated glomerular filtration rate and spot urine albumin to creatinine ratio) are imperative to the diagnosis of CKD