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Activation of these cells stimulates the secretion of somatostatin, a potent inhibitor that acts locally on neighboring -cells to suppress glucagon release (Zheng et al., 2024)
This is one reason Korean brightening systems often outperform Western products for sensitive skin types
increase of glutamate, serotonin, and noradrenaline in the prefrontal cortex
The mechanism by which toxicity results is complex, but is believed to involve reaction between unconjugated NAPQI and critical proteins as well as increased susceptibility to oxidative stress caused by the depletion of glutathione
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