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All authors critically revised the manuscript and approved the final version

Despite the encouraging results of GLP-1/glucagon co-agonism in experimental models, different GLP-1 and glucagon co-agonists have shown various levels of efficacy and tolerability in people with obesity and/or T2D, in early phase clinical trials, which may be explained by the different ratio of GLP-1 to glucagon activity between the different molecules [65]

Zarin said it would be appropriate to follow the authors suggestion that the next step in their research should be to perform studies to assess whether GLP-1 levels in the joint fluid are correlated with the arthritic condition

Unlike many eye conditions that develop gradually, NAION can appear overnight

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