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BMD measurements were available for 158 to 161 participants at week 52

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Many people report more pronounced hangover symptoms on retatrutide, likely due to several factors: prolonged exposure to acetaldehyde (the toxic intermediate in alcohol metabolism), extended gastric emptying time creating prolonged GI distress, dehydration effects amplified by the medications impact on kidney function, and the general nausea tendency of GLP-1 agonists being triggered by alcohols aftereffects

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