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One study covered in the review found that a topical containing Syn-Ake resulted in a 52% reduction in wrinkle size after 28 days of use.34 (As an interesting side note, you may have noticed that Syn-Ake kind of looks or sounds like the word snake. This is because the synthetic peptide Syn-Ake is an analog of a natural one called Waglerin-1, which is derived from the venom of the Southeast Asian temple viper.)34 As with Allies of Skin, much of the research behind the ingredients in The Ordinarys product is positive

Rather than directly suppressing inflammation or repairing tissue, it works at the level of immune system regulation, promoting the development and function of regulatory T cells that keep autoimmune responses in check

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You might find that the breakouts feel more irritated or persistent than usual