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While there arent currently many prescription medications that directly affect glutamate, there are several companies investigating its potential for treating severe treatment-resistant depression, substance abuse, and obsessive-compulsive disorder

Qin H, Chan MWY, Liyanarachchi S, Balch C, Potter D, Souriraj IJ, Cheng ASL, Agosto-Perez FJ, Nikonova EV, Yan PS, Lin H-J, Nephew KP, Saltz JH, Showe LC, Huang THM, Davuluri RV: An integrative ChIP-chip and gene expression profiling to model SMAD regulatory modules

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According to studies, a potent antioxidant, BPC-157, has been shown to inhibit reactive oxygen species generation in the gastrointestinal system