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This leads to: Excessive muscle loss Fatigue and weakness Hair thinning or shedding (telogen effluvium) Nutrient deficiencies Metabolic slowdown How to prevent this: Track protein intake (minimum 0.7g per pound of body weight daily) Eat protein first at every meal Use protein shakes if whole food feels too filling Dont let the medication be an excuse to skip meals Dehydration: Reduced food intake often means reduced fluid intake

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Monitoring Response Patients or research participants typically notice: Appetite suppression within the first 12 weeks Early satiety and slower gastric emptying by weeks 34 Weight loss trends becoming evident by week 8 Continued improvements in glucose metabolism when paired with semaglutide or tirzepatide Side Effects and Considerations Common side effects include: Nausea Mild gastrointestinal discomfort Constipation Injection site reactions These effects are generally transient and dose-dependent, which is why titration is important