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A high reading doesnt always indicate a problem, but it does have clinical significance depending on context

doi:10.5603/GP.a2020.0173

In an alternative non-canonical pathway, specific components of the autophagy machinery - more specifically microtubule-associated protein 1 A/1B-light chain 3 (LC3) - are conjugated to lipids in the phagosome membrane, aiding in the formation of the phagolysosome, as well as in the efficient degradation of the apoptotic body [16]

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