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The top layer that is getting oxidized, it's the tissue that's getting oxidized

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By defining global and gene-specific DNA 5hmC modifications, we demonstrated that DMF induces 5hmC modifications to influence loci-specific chromatin structure through L2HGDH to reduce the levels of L2HG

Antioxidant activities Scavenging reactive oxygen and nitrogen species Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are highly reactive compounds with the potential to damage DNA, proteins, and lipids in cell membranes