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After 68 weeks, patients in the semaglutide group lost an average of 15% of their baseline body weight, or 33.7 pounds, compared to 2.4%, or 5.7 pounds, in the placebo group

Type 2 diabetes treatment requires comprehensive in-person monitoring like frequent lab tests and glucose management, which are beyond the scope of telehealth

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Melanotan1/MSHlike agonism increases cAMP and PKA signaling, which inhibits NFB activation (via preservation of IB), activates CREB, induces antiinflammatory mediators (e.g., IL10), and suppresses proinflammatory cytokines (TNF, IL1, IL6, IL8, IL12), adhesion molecules, and iNOS